Buy 4-HO-DET Fumarate is a high-purity research chemical (available in powder or pellet form). Laboratories and researchers use it to study tryptamine pharmacology, serotonin 5-HT₂A receptor activation, and psychedelic structure-activity relationships in the 4-substituted tryptamine family.
What is 4-HO-DET?
4-HO-DET (4-Hydroxy-N,N-diethyltryptamine), also known as Ethocin, is a synthetic psychedelic of the tryptamine class. It is the active metabolite of 4-AcO-DET. First synthesized by Alexander Shulgin and documented in TiHKAL, it is known for producing strong visual psychedelic effects with a relatively clear headspace and euphoric quality. Sold strictly for laboratory and research purposes only.
Chemical Properties of Buy 4-HO-DET Fumarate
- IUPAC Name: 3-[2-(Diethylamino)ethyl]-1H-indol-4-ol
- Molecular Formula: C₁₄H₂₀N₂O (free base)
- Molar Mass: 232.32 g/mol (free base)
- Salt Form: Fumarate salt (for improved stability and solubility)
- Appearance: White to off-white or beige crystalline powder
- Solubility: Fumarate salt offers good water solubility; soluble in organic solvents like ethanol or DMSO
- Key Features: 4-hydroxy indole tryptamine with N,N-diethyl substitution.
Effects (Research Observations)
4-HO-DET acts primarily as a 5-HT₂A receptor agonist. Reported research observations include:
- Rich visual effects (color enhancement, geometric patterns, fractals, and tracers)
- Euphoria, mood elevation, and enhanced sensory perception
- Altered thought patterns, introspection, and time distortion
- Onset: 20–60 minutes (oral)
- Duration: 4–7 hours
Important Note: These are not approved medical effects. Risks include nausea, anxiety, psychological distress, increased heart rate, muscle tension, and challenging experiences at higher doses. Strictly for research use only — not for human consumption.
Legality of Buy 4-HO-DET Fumarate
4-HO-DET exists in a controlled or gray-area status in most regions:
- United States: Unscheduled federally in many references but may fall under the Federal Analogue Act if intended for human consumption
- United Kingdom: Class A / Psychoactive Substances Act
- Germany / EU: Often restricted under NPS legislation
- Canada / Australia: Controlled under analog or specific tryptamine laws
Always verify current local laws before any purchase or handling. Vendors sell it exclusively for laboratory/research purposes.
Buy 4-HO-DET Fumarate from trusted research chemical suppliers offering lab-tested, high-purity products with discreet shipping and compliance documentation.




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